Research peptide
ARA-290
Cibinetide (ARA-290), a synthetic helix B surface peptide, supplied as a 10mg lyophilised vial for laboratory research.
Supplier documentation available on request. Independent reports are published where held — see current lab reports.
No reconstitution supplies needed. Bought separately for a standard vial, water, needles and wipes come to £14.
Are you sure you have these? Select them. A standard vial arrives as lyophilised powder. Bacteriostatic water, insulin needles and alcohol wipes are needed to prepare it in the laboratory. Nothing is added unless you tick it.
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Overview
ARA-290, also known as cibinetide, is a synthetic peptide based on the helix B surface of erythropoietin (EPO). It was developed as a non-erythropoietic research analogue for investigating signalling through the innate repair receptor complex.
Published work has examined ARA-290 in receptor-signalling, inflammatory-response and tissue-protection models. It is supplied strictly as a research reference material and is not for human or animal consumption.
ARA-290 and the innate repair receptor
ARA-290 is commonly described in the literature as a selective ligand for the innate repair receptor, a heteromeric receptor complex associated with the erythropoietin receptor (EPOR) and beta-common receptor CD131. Researchers use the peptide to investigate this pathway separately from the classical erythropoietic activity of full-length erythropoietin.
The compound is also referred to as cibinetide or pyroglutamate helix B surface peptide (pHBSP). Its short synthetic structure makes it a useful reference compound in receptor-binding, cell-signalling and comparative peptide studies.
ARA-290 in published research
Preclinical studies have examined ARA-290 in models of inflammatory signalling, cell survival and tissue stress. Exploratory clinical research has also used receptor and peripheral nerve function biomarkers to study the compound's biological activity.
These research findings do not establish a consumer or therapeutic use. North Peptides UK supplies ARA-290 only as a laboratory research material.
Buying ARA-290 in the UK
North Peptides UK holds ARA-290 in the UK for tracked dispatch without an international import wait. This listing contains one 10mg lyophilised vial at supplier-stated purity, stored frozen until dispatch, with supplier documentation available on request where held.
Research areas
- EPOR/CD131 innate repair receptor signalling, studied in vitro
- Inflammatory-response and cytokine signalling in preclinical models
- Cell-survival and tissue-stress pathways in laboratory models
- Peripheral nerve function biomarkers in exploratory research
At a glance
- supplier-stated purity
- UK stocked, 24–48h dispatch after payment
- Stored frozen until dispatch
- Supplier documentation on request
Storage and handling
Supplied as a lyophilised powder in a sealed vial and kept frozen until dispatch. Unopened vials are typically stored at -20°C for the long term and 2-8°C for short periods. After reconstitution, vials are generally refrigerated at 2-8°C, protected from light, and not subjected to repeated freeze-thaw cycles.
Specification
| Compound type | Synthetic helix B surface peptide |
|---|---|
| Molecular formula | C51H84N16O21 |
| Molecular weight | ~1,257.4 g/mol |
| CAS number | 1208243-50-8 |
| Synonyms | Cibinetide, pyroglutamate helix B surface peptide, pHBSP |
| Purity | Supplier stated |
| Form | Lyophilised powder |
| Storage | -20°C long-term; 2-8°C short-term |
Questions
What is ARA-290?
ARA-290, also known as cibinetide, is a synthetic helix B surface peptide based on a region of erythropoietin and developed for research into innate repair receptor signalling.
What is ARA-290 supplied as?
A 10mg lyophilised vial with supplier-stated purity, stored frozen until dispatch. Supplier documentation is available on request where held.
Is ARA-290 the same as erythropoietin?
No. ARA-290 is a short synthetic peptide based on the helix B surface of erythropoietin. It is studied as a non-erythropoietic research analogue and is not erythropoietin itself.
Do you stock ARA-290 in the UK?
Yes. The 10mg vial is UK stocked with dispatch within 24–48 hours of confirmed payment on business days via tracked delivery.
Is ARA-290 for research use only?
Yes. It is supplied strictly for laboratory and scientific research and is not for human or animal consumption.
What is another name for ARA-290?
ARA-290 is also known as cibinetide and as pyroglutamate helix B surface peptide (pHBSP).