Research peptide
KPV
Alpha-MSH fragment tripeptide research compound supplied as a 10mg lyophilised vial.
Supplier documentation available on request. Independent reports are published where held — see current lab reports.
No reconstitution supplies needed. Bought separately for a standard vial, water, needles and wipes come to £14.
Are you sure you have these? Select them. A standard vial arrives as lyophilised powder. Bacteriostatic water, insulin needles and alcohol wipes are needed to prepare it in the laboratory. Nothing is added unless you tick it.
Add £70 more for free UK delivery · free from £100
Also available as: KPV Pen Vial (pre-filled kit)
Overview
KPV is the tripeptide lysine-proline-valine (Lys-Pro-Val), corresponding to the C-terminal fragment of the larger hormone alpha-MSH. It is supplied as a lyophilised powder for laboratory research.
In research it is studied in vitro and in preclinical models for its role in inflammation-related signalling, including NF-kB pathway activity, and in antimicrobial research. It is supplied as a research reference material only and is not for human or animal consumption.
KPV in published research
KPV is the C-terminal tripeptide of alpha-melanocyte-stimulating hormone (alpha-MSH 11-13). Much of the interest in it comes from laboratory work suggesting that this short fragment keeps part of the inflammation-related signalling activity reported for full-length alpha-MSH, while being far smaller and simpler to make.
Published studies describe KPV being taken up into intestinal epithelial cells through the peptide transporter PepT1, where it has been reported to reduce NF-kB and MAPK pathway activation in cell and rodent colitis models. Separate in vitro work has examined its activity against Staphylococcus aureus and Candida albicans, and researchers have used KPV as a model cargo in nanoparticle and hydrogel delivery studies.
Buying KPV in the UK
North Peptides UK holds KPV in stock in the UK and sends it by tracked delivery, so there is no import wait or customs hold. Each vial contains 10mg of lyophilised KPV at supplier-stated purity, kept frozen until it leaves us, and supplier documentation is available on request where held. Bacteriostatic water and insulin needles for reconstitution can be added before checkout.
KPV vial, KPV pen vial or KLOW Stack
This listing is the standard lyophilised vial, which suits researchers who reconstitute to their own concentration. The KPV Pen Vial holds the same tripeptide pre-reconstituted as a 10mg/3ml liquid. KPV is also one of the four components of the KLOW Stack research blend, alongside GHK-Cu, TB-500 and BPC-157.
Research guides
- What Is the KLOW Stack? A Four-Compound Research BlendCompound Guide · 3 min read
Research areas
- NF-kB signalling pathway activity, characterised in inflammation research models
- Pro-inflammatory cytokine (IL-6, TNF-alpha) signalling, studied in vitro
- Antimicrobial-activity research models
- Gastrointestinal inflammation research models
At a glance
- supplier-stated purity
- UK stocked, 24–48h dispatch after payment
- Stored frozen until dispatch
- Supplier documentation on request
Storage and handling
Supplied as a lyophilised powder in a sealed vial and kept frozen until dispatch. Unopened vials are typically stored at -20°C for the long term and 2-8°C for short periods. After reconstitution, vials are generally refrigerated at 2-8°C, protected from light, and not subjected to repeated freeze-thaw cycles.
Specification
| Compound type | Alpha-MSH C-terminal fragment tripeptide |
|---|---|
| Sequence | Lys-Pro-Val |
| Molecular formula | C16H30N4O4 |
| Molecular weight | ~342.4 g/mol |
| CAS number | 67727-97-3 |
| Synonyms | Lysyl-prolyl-valine |
| Purity | Supplier stated |
| Form | Lyophilised powder |
| Storage | -20°C long-term; 2-8°C short-term |
Questions
What is KPV?
The tripeptide lysine-proline-valine (Lys-Pro-Val), corresponding to the C-terminal fragment of the hormone alpha-MSH, supplied as a 10mg lyophilised vial for research.
What is KPV supplied as?
A 10mg lyophilised vial with supplier-stated purity, stored frozen until dispatch. Supplier documentation is available on request where held.
Do you stock KPV in the UK?
Yes. It is UK stocked with dispatch within 24–48 hours of confirmed payment on business days via tracked delivery.
Is KPV for research use only?
Yes. It is supplied strictly for laboratory research and is not for human or animal consumption.
Is KPV the same as alpha-MSH?
No. KPV is only the last three amino acids (Lys-Pro-Val) of the 13-amino-acid hormone alpha-MSH. It is studied as a compound in its own right because it is far smaller and simpler to synthesise than the full hormone.
What is the difference between the KPV vial and the KPV pen vial?
The vial is 10mg of lyophilised powder that you reconstitute yourself. The KPV Pen Vial holds the same tripeptide already reconstituted as a 10mg/3ml liquid in a pen-compatible vial, supplied with a disposable research pen.
Where can I buy KPV peptide in the UK?
North Peptides UK stocks KPV in the UK as a 10mg lyophilised vial and as a 10mg/3ml pen vial, both sent by tracked delivery within 24–48 hours of confirmed payment.
